Week 12 is jam-packed with football action. No teams are on a bye, and from a Thanksgiving triple-header to a Black Friday game to Sunday's slate of games ahead of Monday Night Football, it's an exciting week for football fans.
Concluding Thanksgiving action is an NFC West matchup between two of the teams fighting for the top of the division: the Seattle Seahawks (6-4) and the San Francisco 49ers (7-3). A Seahawks win give them the division lead, while the 49ers can maintain their first place standing with a win.
Here's what to know going into Thursday night's game.
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Seattle Seahawks vs. San Francisco 49ers predictions
The Arizona Republic: 49ers 27, Seahawks 20
Jeremy Cluff writes, "The Seahawks are tough at home, but the 49ers seem to have their moxie back. This could be close, but San Francisco's defense will make a key play or two late."
NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.
All 49ers (Sports Illustrated FanNation): Confident in a 49ers victory
Mark Lammey wrties, "Not only have the 49ers looked as hot as ever after their bye week, but the Seahawks have also been looking rough ever since the 37-3 beatdown they received courtesy of the Baltimore Ravens... [the 49ers] aren’t even allowing Seattle to keep things close. With that in mind, we’ll confidently make our best 49ers vs. Seahawks prediction on San Francisco ML."
VSiN.com: Lay the points for San Francisco
Zachary Cohen writes, "When I first saw the line on this game, I thought the Seahawks might be getting too many points for a game in Seattle. However, the more you look at the statistical profiles of both of these teams, it’s hard not to like San Francisco to win somewhat comfortably. The recent head-to-head history is just a cherry on top. So, I’d suggest laying the points, even on the road."
Winners and Whiners: 49ers will win and cover
Mark Ruelle writes, "Playing the Niners, especially as they are playing right now, is hard enough but trying to compete against them with a banged-up squad is more than this Seahawks team can handle. Purdy was right at home last season in the team's win at Seattle, a legendarily challenging home-field advantage, so I don't expect him to have difficulties on Thursday night either. Look for the Niners to pick up a double-digit win here."
ESPN: 49ers have a 73.3% chance to win
ESPN Analytics make San Francisco a heavy favorite on the road, leaving Seattle with just a 26.5% chance to take the victory at home.
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Thursday Night Football: Odds, betting lines for 49ers at Seahawks Thanksgiving game
The 49ers are favorites to defeat the Seahawks, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.
All odds as of Wednesday morning.
- Spread: 49ers (-7)
- Moneyline: 49ers (-350); Seahawks (+260)
- Over/under: 43
Seahawks vs. 49ers: How to watch Thanksgiving football game
When: Thursday, Nov. 23, 8:20 p.m. ET
Where: Lumen Field, Seattle, Wash.
Cable TV: NBC
Streaming: Peacock; YouTube TV; FuboTV
How to watch:Catch NFL action with a Fubo subscription
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Seahawks vs. 49ers: Predictions, picks, odds for TNF Thanksgiving game - USA TODAY
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